The extracellular matrix (ECM) provides cues to direct mammogenesis, tumourigenesis and metastatic processes.Over the past several decades, two-dimensional (2D) culture models have been invaluable in furthering our understanding of the tumor microenvironment (TME), however, they still do not accurately emulate the associated biological complexities
Median arcuate ligament syndrome, a rare case of chronic abdominal pain
The median arcuate ligament syndrome (MALS) is a rare disease characterized by abdominal pain caused by the external compression of the celiac artery by the median arcuate ligament.Surgical Card Games treatment is indicated, but given the non-specific symptoms, these patients are often hospitalized in the Departments of Internal Medicine where the
Effect of post-harvest ripening and drying methods on seed quality and storability in pumpkin cv Pusa Hybrid 1
An investigation was carried out, to study the effect of post-harvest ripening and drying methods on the seed quality in pumpkin cv Pusa Hybrid 1, during summer 2008 and 2009 at Seed Production Unit, IARI, New Delhi.After harvesting, the fruits were allowed for post-harvest ripening (PHR) of zero days Beauty (P0), 10 days (P1) and 20 days (P2) and
An Optimized Procedure to Estimate the Economic Seismic Losses of Existing Reinforced Concrete Buildings due to Seismic Damage
The latest Italian seismic events have highlighted a high discrepancy between the potential destructiveness of an earthquake and the consequent economic losses due to damage to buildings.The main reason for this mismatch is the high number of vulnerable residential buildings or the low-to-medium vulnerability of buildings that are reaching the ends
An orifice shape-based reduced order model of patient-specific mitral valve regurgitation
Mitral valve regurgitation (MR) is one of the most prevalent valvular heart diseases.Its quantitative assessment is challenging but crucial for treatment decisions.Using computational fluid dynamics (CFD), we developed a reduced order model (ROM) describing the relationship between MR flow rates, transvalvular pressure differences, and the size and